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Spatial Configuration of Pancreatic Cancer Is Associated with Disease Recurrence after Neoadjuvant Therapy and Curative-Intent Resection.

Luis H Cisneros, Merih D Toruner, Zafar Siddiqui, Andrea V Maraone, Miranda Lin, Alex Xiao, Cornelius Thiels, Mark J Truty, Ben George, Khalid Jazieh, Robb Scheel, Robert R McWilliams, Carlo C Maley, Chris Hartley, Rofyda Elhalaby, Paul Dizona, Qian Shi, Martin E Fernandez-Zapico, Ryan M Carr

Clinical cancer research : an official journal of the American Association for Cancer ResearchSep 15, 2026PMID 42456051doi:10.1158/1078-0432.CCR-25-4968 PMC13525901Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 18, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260918-000001
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PURPOSE: Pancreatic ductal adenocarcinoma (PDAC) frequently recurs after neoadjuvant therapy (NT) and curative-intent resection. Although major pathologic response predicts favorable outcomes, most patients achieve only minor response with a heterogeneous recurrence risk. We asked whether the…

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