Publication
"Alkaline-Hammer Strategy" Breaks Acidic and Stromal Barriers to Induce Alkaliptosis and Enhance Immunotherapy in Pancreatic Cancer.
Wei Liu, Yilong Li, Kuo He, Wenda Jiang, Jiajun Li, Xin Zheng, Qiyuan Li, Tieyuan Sun, Jialin Ren, Jixin Liang, Hua Chen, Yongwei Wang, Chunfa Yang, Jiandong Wu, Bei Sun, Xinlong Wang, Ping'an Ma
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- PubMed
- Retrieved
- Sep 17, 2026
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- normalized (units and labels harmonized; values unchanged)
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- ING-PUBMED-20260917-000001
Abstract
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Immunotherapy for pancreatic cancer remains a formidable challenge due to the highly immunosuppressive tumor microenvironment (TME), characterized by dense stromal barriers and acidic niches that collectively restrict drug delivery and antitumor immunity. Here, we propose an "Alkaline-Hammer"…
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- cancerMalignant Pancreatic Neoplasmdictionary0.60
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