Publication
Intraperitoneal delivery of the oncolytic virus CF17 improves tumor immunogenicity and survival in gastric cancer peritoneal metastasis.
Zhifang Zhang, Annie Yang, Anthony K Park, Shyambabu Chaurasiya, Sang-In Kim, Jianming Lu, Isabel Monroy, Hannah Valencia, Courtney Chen, Supriya Deshpande, Yuman Fong, Yanghee Woo
- Source
- PubMed
- Retrieved
- Sep 19, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260919-000001
Abstract
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Peritoneal metastasis (PM) is the leading cause of treatment failure and death from gastric cancer (GC). We evaluated the antitumor and immunogenic effects of CF17, an oncolytic chimeric orthopoxvirus, in a novel syngeneic mouse model of GCPM. CF17 was tested in mouse GC cell lines (ACKPY3944 and…
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- cancerMalignant Gastric Neoplasmdictionary0.60
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