Publication
Non-Invasive Transdermal Delivery of miR-30a-5p via MUC1-Aptamer-Guided Tetrahedral DNA Nanostructures for Gene Silencing in Cutaneous Melanoma.
Zhou Jiang, Ziqi Yue, Jiale Liang, Yichen Yang, Yuxuan Zhao, Ye Chen, Long Bai, Ruiqing Wang, Songhang Li, Yunfeng Lin
Small (Weinheim an der Bergstrasse, Germany)Sep 1, 2026PMID 42429187doi:10.1002/smll.74557 PMC13533276Journal ArticleResearch Support, Non-U.S. Gov'tpubmedProvenance
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- Sep 26, 2026
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Abstract
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Cutaneous malignant melanoma is a highly aggressive skin cancer with poor prognosis. Although microRNA (miRNA)-based gene therapy shows promise, its clinical translation is limited by rapid degradation in serum and the barrier function of the stratum corneum. Herein, we engineer a programmable,…
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- cancerCutaneous Melanomadictionary0.60
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