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Leonurine inhibits the proliferation and metastasis of liver cancer cells by regulating the PI3K/AKT signaling pathway via epithelial‑mesenchymal transition.

Bowen Hu, Maher Al Hussan, Jiakai Zhang, Peihao Wen, Changjun Huang, Yang Chen, Huanfei Ding

Molecular medicine reportsSep 1, 2026PMID 42429151doi:10.3892/mmr.2026.13961 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 10, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260910-000001
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Hepatocellular carcinoma (HCC) remains a major global health burden, characterized by limited therapeutic options and poor prognosis. The present study aimed to evaluate the anticancer potential of leonurine, a natural alkaloid derived from Leonurus japonicus, in HCC. Through an integrated approach…

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