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Multiplex RT-PCR-Based Sequencing Assay to Detect Kidney Cancer-Specific Splice Variants in Tumor Tissues and Plasma Cell-Free RNAs.

Kapil K Avasthi, Kendrick H Yim, Youngchul Kim, Paola M Ramos Echevarria, Liz M Darst, Nicholas Abreu, Kelly P Zea, Mitchell T Hayes, Aram Vosoughi, Brandon J Manley, Liang Wang

Molecular diagnosis & therapySep 1, 2026PMID 42410176doi:10.1007/s40291-026-00865-2 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 29, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260929-000001
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BACKGROUND: Clear cell renal cell carcinoma (ccRCC) lacks sensitive molecular biomarkers for early detection of disease recurrence and monitoring. Recurrent splice variants (SVs) offer promising diagnostic potential for capturing tumor-specific signals in circulating blood. In this study, we report…

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