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The importance of HPV testing in oropharyngeal cancer in two US populations.

M M Lawas, M Hsieh, S Patil, E Mohebbi, R Zhang, J Ahn, W Benjamin, S B Chinn, M Witek, B Mabvakure, A Duttargi, L M Cruz, B Garb, S Li, N J D'Silva, M A Sartor, L S Rozek

Neoplasia (New York, N.Y.)Sep 1, 2026PMID 42391786doi:10.1016/j.neo.2026.101323 PMC13352036Journal ArticleResearch Support, N.I.H., ExtramuralpubmedProvenance
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PubMed
Retrieved
Sep 30, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260930-000001
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BACKGROUND: HPV-positive (HPV+) oropharyngeal squamous cell carcinoma (OPSCC) patients have improved survival compared to HPV-negative OPSCC (HPV-) patients (5-year survival rates of ∼80% versus ∼40%). The predictive value of p16 immunohistochemistry (IHC) for HPV+ OPSCC, the most widely used…

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