Publication
PARP7 inhibitors enhance the immunogenic effects of radiation in pancreatic cancer cells.
Niccolò Bragato, Ana Beatriz Dias, Anna Ohradanova-Repic, Alma Dupanovic, Filip Horvat, Patrick Fischer, Lisa-Marie Appel, Lena Walch, Ava Kleinwächter, Anna Röhrer, Sylvia Kerschbaum-Gruber, Sandra Barna, Piero Fossati, Dietmar Georg, Joachim Widder, Klaus Podar, Michael Cohen, Dea Slade
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- PubMed
- Retrieved
- Sep 19, 2026
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- normalized (units and labels harmonized; values unchanged)
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- ING-PUBMED-20260919-000001
Abstract
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Pancreatic ductal adenocarcinoma (PDAC) is the most frequent type of pancreatic cancer with a poor prognosis and resistance to conventional radio- and chemotherapy. Radiation can induce pro-inflammatory signaling by activating the type 1 interferon (IFN-I) response, which can be enhanced by…
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- cancerMalignant Pancreatic Neoplasmdictionary0.60
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