Publication
Redirected T-cell cytotoxicity identifies BRD9-PTGES axis as an immune-sensitising vulnerability in ovarian cancer.
Shanni Guo, Peng Shi, Changrui Yang, Shuyi Qian, Fan Yang, Xia Yin, Bowen Sun
Biochemical and biophysical research communicationsSep 3, 2026PMID 42349121doi:10.1016/j.bbrc.2026.154180 Journal ArticlepubmedProvenance
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- Sep 11, 2026
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- ING-PUBMED-20260911-000001
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Ovarian cancer shows limited responsiveness to immune checkpoint blockade, suggesting that malignant cells harbor intrinsic programs capable of suppressing T cell-mediated antitumor immunity. To uncover these programs under fixed recognition signal conditions, the research team established and…
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- cancerMalignant Ovarian Neoplasmdictionary0.60
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