Publication
Targeting microtubule dynamics: synthesis and evaluation of novel 4-thiazolidinone derivatives in pancreatic Cancer.
Rostyslav Dudchak, Serhii Holota, Magdalena Podolak, Olga Klaudia Szewczyk-Roszczenko, Ihor Yushyn, Nazar Solodyak, Olexandr Karpenko, Robert Czarnomysy, Agnieszka Gornowicz, Małgorzata Borzym-Kluczyk, Yegor Vassetzky, Anna Bielawska, Krzysztof Bielawski, Roman Lesyk
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- PubMed
- Retrieved
- Sep 18, 2026
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- normalized (units and labels harmonized; values unchanged)
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- ING-PUBMED-20260918-000001
Abstract
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Pancreatic cancer remains one of the most lethal malignancies, with limited therapeutic options and high chemoresistance partly associated with β-tubulin overexpression. In this study, we synthesized and biologically evaluated a series of 4-thiazolidinone derivatives, identifying Les-6666 and…
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- cancerMalignant Pancreatic Neoplasmdictionary0.60
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