Publication
CAR T-cell therapy as a definitive consolidation for older adults with B-ALL in first complete remission.
Ibrahim Aldoss, Lior Goldberg, Jianying Zhang, Andrew Artz, Mary C Clark, Min Guan, Ruby Espinosa, Thiruvaimozhi Abimannan, Jiaqi Wu, Bryan Garcia, Eric R Haas, Khyatiben V Pathak, Brooke Lovell, Patrick Pirrotte, Vaibhav Agrawal, Neguine Sanani, Stephanie Kasten, Dileshni Tilakawardane, Jamie R Wagner, Jinny Paul, Haoyue Shan, Samer Khaled, Lihua E Budde, Paul Koller, Anthony S Stein, Vinod Pullarkat, Amandeep Salhotra, Ahmed Aribi, Guido Marcucci, Xiuli Wang, Stephen J Forman
- Source
- PubMed
- Retrieved
- Sep 19, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260919-000001
Abstract
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We report a phase 1 study assessing the safety and efficacy of CD19 chimeric antigen receptor (CAR) T cells as definitive consolidation in older adults (aged ≥55 years) with B-cell acute lymphoblastic leukemia (B-ALL) in first complete remission (CR1). Eighteen patients received lymphodepletion…
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Validated 2
- trialNCT02146924registry_reference1.00
- trialNCT05707273registry_reference1.00
Registered trialsNCT02146924NCT05707273
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