Publication
Safe Accelerated Venetoclax Escalation: a phase 1b study of obinutuzumab plus venetoclax with daily ramp-up in CLL.
Jennifer L Crombie, Inhye E Ahn, Yue Ren, Svitlana Tyekucheva, Celeste Carey, Mari Kniezewski, Samantha Normilus, Shantal Solomon, Josie Montegaard, Austin I Kim, Reid W Merryman, Philippe Armand, David C Fisher, Jennifer R Brown, Matthew S Davids
- Source
- PubMed
- Retrieved
- Sep 19, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260919-000001
Abstract
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Although venetoclax-based regimens are highly effective for patients with chronic lymphocytic leukemia (CLL), initiation is complex because of the requirement of a 5-week dose ramp-up used to mitigate the risk of tumor lysis syndrome (TLS). We report the results of the first prospective study of…
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- trialNCT04843904registry_reference1.00
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