Publication
Development of super Vδ2 T cells for relapsed/refractory acute myeloid Leukemia via non-viral site-specific integration.
Li Liu, Hanlu Wang, Lin Shi, Chao Zhang, Leshuai Zhang, Lulu Lv, Yongzeng Wang
International immunopharmacologySep 15, 2026PMID 42284763doi:10.1016/j.intimp.2026.116981 Journal ArticlepubmedProvenance
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- Sep 29, 2026
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- ING-PUBMED-20260929-000001
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The efficacy of chimeric antigen receptor (CAR)-T cell therapy in relapsed/refractory acute myeloid leukemia (R/R AML) is limited by tumor heterogeneity, antigen evasion, and treatment-related toxicities. Gamma delta (γδ) T cells mediate antitumor activity independent of MHC by sensing…
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