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Low-intensity induction chemotherapy before chemoradiotherapy for rectal cancer: 10-year overall survival in the LARC-RRP trial.

Anne Hansen Ree, Sebastian Meltzer, Kjersti Flatmark, Svein Dueland

The British journal of radiologyOct 1, 2026PMID 42233285doi:10.1093/bjr/tqag133 PMC13623223Journal ArticlepubmedProvenance
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PubMed
Retrieved
Oct 2, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20261002-000001
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OBJECTIVES: Total neoadjuvant therapy (TNT) for locally advanced rectal cancer (LARC) often uses intensive oxaliplatin-based chemotherapy alongside standard radiotherapy to prevent metastatic progression. The optimal intensity of the chemotherapy component, given a contribution of radiotherapy to…

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