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Treatment Adequacy and Baseline Risk Modify the Association Between Adjuvant Chemotherapy and Survival After Pathological Complete Response in Rectal Cancer.

Chentong Wang, Xiao Zhang, Yang An, Chunkang Liu, Bin Wu, Yi Xiao, Junyang Lu, Guole Lin

International journal of cancerSep 15, 2026PMID 42144888doi:10.1002/ijc.70505 PMC13397233Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 26, 2026
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normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260926-000001
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The role of adjuvant chemotherapy (ACT) in patients with locally advanced rectal cancer (LARC) who achieve pathological complete response (pCR) after neoadjuvant chemoradiotherapy (nCRT) remains controversial, and it is unclear whether pCR represents a uniformly low-risk state with respect to…

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