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Fragment of esophageal cancer-related gene-4 induces lysosome-dependent cell death via cathepsin secretion in astrocytes.

Naoto Oikawa, Lifu Zhang, Toru Kondo

Tissue & cellOct 1, 2026PMID 42048726doi:10.1016/j.tice.2026.103553 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Oct 2, 2026
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normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20261002-000001
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Esophageal cancer-related gene-4 (ECRG4) is a hormone-like protein that acts as a tumor suppressor by inducing cell death through apoptosis and cell-cycle arrest. ECRG4 is expressed in various organs, including the brain, and it influences the viability and function of neural cells such as…

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