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Efficacy of pegfilgrastim in preventing febrile neutropenia during DCF chemotherapy for esophageal cancer: A systematic review and meta-analysis.

Khaled Hemdan, Rana Mohamed El Tabakh, Ziad W Elmezayen, Amr Mahmoud Yousef, Ahmed Hussein, Ali M Elghareab, Mazen Momtaz Shehata, Alaa Abdelaziz Ellethey, Ahmed Oun

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy PractitionersOct 1, 2026PMID 41610170doi:10.1177/10781552261416090 Journal ArticleMeta-AnalysisSystematic ReviewpubmedProvenance
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PubMed
Retrieved
Oct 2, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20261002-000001
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BackgroundEsophageal cancer remains a leading cause of cancer-related mortality worldwide, with docetaxel, cisplatin, and fluorouracil (DCF) chemotherapy being a standard treatment option for locally advanced disease. However, DCF is associated with a high incidence of febrile neutropenia (FN), a…

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