IFN-Gamma Expression as a Predictor of Response to Immune Checkpoint Inhibitors in First-Line Metastatic Melanoma

COMPLETED

Identifier: CI-TRIAL-00104376
Entity page: /trial/NCT07436390 ↗
Edges: 6

Neighbours: 2 cancers3 drugs
Drawn: 5 of 5 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
IFN-Gamma Expression as a Predictor of Response to Immune Checkpoint Inhibitors in First-Line Metastatic Melanoma condition of …CONDITION_OFderived3 of 3
← condition of	Malignant Skin Neoplasm registry condition “Skin Cancer” mapped ALIAS	—	—	Malignant Skin Neoplasm	1	Observed	clinicaltrials	graph →
← condition of	Melanoma registry condition “Malignant Melanoma” mapped ALIAS	—	—

IFN-Gamma Expression as a Predictor of Response to Immune Checkpoint Inhibitors in First-Line Metastatic Melanoma intervention of …INTERVENTION_OFderived3 of 3
← intervention of	Ipilimumab/Nivolumab Regimen registry intervention “Ipilimumab/Nivolumab” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Nivolumabmonoclonal antibody registry intervention “Nivolumab” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Pembrolizumabmonoclonal antibody registry intervention “Pembrolizumab” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

IFN-Gamma Expression as a Predictor of Response to Immune Checkpoint Inhibitors in First-Line Metastatic Melanoma intervention of …INTERVENTION_OFderived3 of 3

← intervention of

Ipilimumab/Nivolumab Regimen

registry intervention “Ipilimumab/Nivolumab” (DRUG) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Nivolumabmonoclonal antibody

registry intervention “Nivolumab” (DRUG) mapped ALIAS

—