Pressurized Intraperitoneal Aerosolized Chemotherapy With Mitomycin for the Treatment of Unresectable Appendix or Colorectal Cancer With Peritoneal Metastases, The IMPACT Trial

RECRUITING

Identifier: CI-TRIAL-00123335
Entity page: /trial/NCT07271355 ↗
Edges: 10

Neighbours: 3 cancers5 drugs
Drawn: 8 of 8 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Pressurized Intraperitoneal Aerosolized Chemotherapy With Mitomycin for the Treatment of Unresectable Appendix or Colorectal Cancer With Peritoneal Metastases, The IMPACT Trial condition of …CONDITION_OFderived5 of 5
← condition of	Appendix Carcinoma registry condition “Metastatic Appendix Carcinoma” mapped CURATED_BROADER	—	—	Appendix Carcinoma	1	Observed	clinicaltrials	graph →
← condition of	Appendix Carcinoma registry condition “Stage IV Appendix Carcinoma AJCC v8” mapped CURATED_BROADER

Pressurized Intraperitoneal Aerosolized Chemotherapy With Mitomycin for the Treatment of Unresectable Appendix or Colorectal Cancer With Peritoneal Metastases, The IMPACT Trial intervention of …INTERVENTION_OFderived5 of 5
← intervention of	Bevacizumabmonoclonal antibody registry intervention “Bevacizumab” (BIOLOGICAL) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Fluorouracilsmall molecule registry intervention “Fluorouracil” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Irinotecansmall molecule registry intervention “Irinotecan Hydrochloride” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Leucovorinsmall molecule registry intervention “Leucovorin Calcium” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Mitomycinsmall molecule registry intervention “Mitomycin” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Pressurized Intraperitoneal Aerosolized Chemotherapy With Mitomycin for the Treatment of Unresectable Appendix or Colorectal Cancer With Peritoneal Metastases, The IMPACT Trial intervention of …INTERVENTION_OFderived5 of 5

← intervention of

Bevacizumabmonoclonal antibody

registry intervention “Bevacizumab” (BIOLOGICAL) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Fluorouracilsmall molecule

registry intervention “Fluorouracil” (DRUG) mapped ALIAS

—