Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer

RECRUITING

Identifier: CI-TRIAL-00108435
Entity page: /trial/NCT06179303 ↗
Edges: 10

Neighbours: 2 cancers6 drugs
Drawn: 8 of 8 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer condition of …CONDITION_OFderived4 of 4
← condition of	HER2-Negative Breast Carcinoma registry condition “Locally Advanced Unresectable HER2-Negative Breast Carcinoma” mapped CURATED_BROADER	—	—	HER2-Negative Breast Carcinoma	1	Observed	clinicaltrials	graph →
← condition of	HER2-Negative Breast Carcinoma registry condition “Metastatic HER2-Negative Breast Carcinoma” mapped CURATED_BROADER

Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer intervention of …INTERVENTION_OFderived6 of 6
← intervention of	Abemaciclibsmall molecule registry intervention “Abemaciclib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Anastrozolesmall molecule registry intervention “Anastrozole” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Exemestanesmall molecule registry intervention “Exemestane” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Fulvestrantsmall molecule registry intervention “Fulvestrant” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Letrozolesmall molecule registry intervention “Letrozole” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Tamoxifensmall molecule registry intervention “Tamoxifen” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer intervention of …INTERVENTION_OFderived6 of 6

← intervention of

Abemaciclibsmall molecule

registry intervention “Abemaciclib” (DRUG) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Anastrozolesmall molecule

registry intervention “Anastrozole” (DRUG) mapped ALIAS

—