Study of an Anti-HER3 Antibody, HMBD-001, With or Without Chemotherapy in Patients With Solid Tumors Harboring an NRG1 Fusion or HER3 Mutation

ACTIVE NOT RECRUITING

Identifier: CI-TRIAL-00088671
Entity page: /trial/NCT05919537 ↗
Edges: 7

Neighbours: 3 cancers3 drugs
Drawn: 6 of 6 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Study of an Anti-HER3 Antibody, HMBD-001, With or Without Chemotherapy in Patients With Solid Tumors Harboring an NRG1 Fusion or HER3 Mutation condition of …CONDITION_OFderived4 of 4
← condition of	Lung Non-Small Cell Carcinoma registry condition “Non-Small Cell Lung Cancer” mapped ALIAS	—	—	Lung Non-Small Cell Carcinoma	1	Observed	clinicaltrials	graph →
← condition of	Malignant Pancreatic Neoplasm registry condition “Pancreatic Cancer” mapped CURATED_EXACT

Study of an Anti-HER3 Antibody, HMBD-001, With or Without Chemotherapy in Patients With Solid Tumors Harboring an NRG1 Fusion or HER3 Mutation intervention of …INTERVENTION_OFderived3 of 3
← intervention of	Docetaxelsmall molecule registry intervention “Docetaxel” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Gemcitabinesmall molecule registry intervention “Gemcitabine” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Nab-paclitaxel registry intervention “Nab-paclitaxel” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Study of an Anti-HER3 Antibody, HMBD-001, With or Without Chemotherapy in Patients With Solid Tumors Harboring an NRG1 Fusion or HER3 Mutation intervention of …INTERVENTION_OFderived3 of 3

← intervention of

Docetaxelsmall molecule

registry intervention “Docetaxel” (DRUG) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Gemcitabinesmall molecule

registry intervention “Gemcitabine” (DRUG) mapped ALIAS

—