Tucatinib Plus Trastuzumab and Oxaliplatin-based Chemotherapy or Pembrolizumab-containing Combinations for HER2+ Gastrointestinal Cancers

ACTIVE NOT RECRUITING

Identifier: CI-TRIAL-00103967
Entity page: /trial/NCT04430738 ↗
Edges: 12

Neighbours: 5 cancers7 drugs
Drawn: 12 of 12 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Tucatinib Plus Trastuzumab and Oxaliplatin-based Chemotherapy or Pembrolizumab-containing Combinations for HER2+ Gastrointestinal Cancers condition of …CONDITION_OFderived5 of 5
← condition of	Cholangiocarcinoma registry condition “Cholangiocarcinoma” mapped ONTOLOGY_EXACT	—	—	Cholangiocarcinoma	1	Observed	clinicaltrials	graph →
← condition of	Colorectal Carcinoma registry condition “Colorectal Carcinoma” mapped ONTOLOGY_EXACT	—

Tucatinib Plus Trastuzumab and Oxaliplatin-based Chemotherapy or Pembrolizumab-containing Combinations for HER2+ Gastrointestinal Cancers intervention of …INTERVENTION_OFderived7 of 7
← intervention of	Capecitabinesmall molecule registry intervention “capecitabine” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Fluorouracilsmall molecule registry intervention “fluorouracil” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Leucovorinsmall molecule registry intervention “leucovorin” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Oxaliplatinsmall molecule registry intervention “oxaliplatin” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Pembrolizumabmonoclonal antibody registry intervention “pembrolizumab” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Trastuzumabmonoclonal antibody registry intervention “trastuzumab” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Tucatinibsmall molecule registry intervention “tucatinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Tucatinib Plus Trastuzumab and Oxaliplatin-based Chemotherapy or Pembrolizumab-containing Combinations for HER2+ Gastrointestinal Cancers intervention of …INTERVENTION_OFderived7 of 7

← intervention of

Capecitabinesmall molecule

registry intervention “capecitabine” (DRUG) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Fluorouracilsmall molecule

registry intervention “fluorouracil” (DRUG) mapped ALIAS

—