Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma

COMPLETED

Identifier: CI-TRIAL-00109119
Entity page: /trial/NCT04396860 ↗
Edges: 5

Neighbours: 2 cancers3 drugs
Drawn: 5 of 5 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma condition of …CONDITION_OFderived2 of 2
← condition of	Gliosarcoma registry condition “Gliosarcoma” mapped ONTOLOGY_EXACT	—	—	Gliosarcoma	1	Observed	clinicaltrials	graph →
← condition of	MGMT-Unmethylated Glioblastoma registry condition “MGMT-Unmethylated Glioblastoma” mapped ONTOLOGY_EXACT

Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma intervention of …INTERVENTION_OFderived3 of 3
← intervention of	Ipilimumabmonoclonal antibody registry intervention “Ipilimumab” (BIOLOGICAL) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Nivolumabmonoclonal antibody registry intervention “Nivolumab” (BIOLOGICAL) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Temozolomidesmall molecule registry intervention “Temozolomide” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma intervention of …INTERVENTION_OFderived3 of 3

← intervention of

Ipilimumabmonoclonal antibody

registry intervention “Ipilimumab” (BIOLOGICAL) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Nivolumabmonoclonal antibody

registry intervention “Nivolumab” (BIOLOGICAL) mapped ALIAS

—