Ivosidenib and Combination Chemotherapy for the Treatment of IDH1 Mutant Relapsed or Refractory Acute Myeloid Leukemia

TERMINATED

Identifier: CI-TRIAL-00113178
Entity page: /trial/NCT04250051 ↗
Edges: 13

Neighbours: 3 cancers5 drugs
Drawn: 8 of 8 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Ivosidenib and Combination Chemotherapy for the Treatment of IDH1 Mutant Relapsed or Refractory Acute Myeloid Leukemia condition of …CONDITION_OFderived7 of 7
← condition of	Acute Myeloid Leukemia registry condition “Refractory Acute Myeloid Leukemia” mapped CURATED_BROADER	—	—	Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →
← condition of	Acute Myeloid Leukemia registry condition “Newly Diagnosed Acute Myeloid Leukemia (AML)” mapped CURATED_BROADER

Ivosidenib and Combination Chemotherapy for the Treatment of IDH1 Mutant Relapsed or Refractory Acute Myeloid Leukemia intervention of …INTERVENTION_OFderived6 of 6
← intervention of	Cytarabinesmall molecule registry intervention “Cytarabine” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Filgrastimother registry intervention “Filgrastim” (BIOLOGICAL) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Fludarabinesmall molecule registry intervention “Fludarabine” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Fludarabinesmall molecule registry intervention “Fludarabine Phosphate” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Idarubicinsmall molecule registry intervention “Idarubicin” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Ivosidenibsmall molecule registry intervention “Ivosidenib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Ivosidenib and Combination Chemotherapy for the Treatment of IDH1 Mutant Relapsed or Refractory Acute Myeloid Leukemia intervention of …INTERVENTION_OFderived6 of 6

← intervention of

Cytarabinesmall molecule

registry intervention “Cytarabine” (DRUG) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Filgrastimother

registry intervention “Filgrastim” (BIOLOGICAL) mapped ALIAS

—