Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

TERMINATED

Identifier: CI-TRIAL-00074645
Entity page: /trial/NCT03878524 ↗
Edges: 96

Neighbours: 11 cancers15 drugs
Drawn: 26 of 26 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial condition of …CONDITION_OFderived15 of 44show all (up to 200)
← condition of	Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive registry condition “Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive” mapped ALIAS	—	—	Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive	1	Observed	clinicaltrials	graph →
condition of

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial intervention of …INTERVENTION_OFderived15 of 52show all (up to 200)
← intervention of	Abemaciclibsmall molecule registry intervention “Abemaciclib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Abirateronesmall molecule registry intervention “Abiraterone” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Afatinibsmall molecule registry intervention “Afatinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Bevacizumabmonoclonal antibody registry intervention “Bevacizumab” (BIOLOGICAL) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Bicalutamidesmall molecule registry intervention “Bicalutamide” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Bortezomibsmall molecule registry intervention “Bortezomib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Cabazitaxelsmall molecule registry intervention “Cabazitaxel” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Cabozantinibsmall molecule registry intervention “Cabozantinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Capecitabinesmall molecule registry intervention “Capecitabine” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Carboplatinsmall molecule registry intervention “Carboplatin” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Celecoxibsmall molecule registry intervention “Celecoxib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Cobimetinibsmall molecule registry intervention “Cobimetinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Copanlisibsmall molecule registry intervention “Copanlisib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Dabrafenibsmall molecule registry intervention “Dabrafenib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Darolutamidesmall molecule registry intervention “Darolutamide” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial intervention of …INTERVENTION_OFderived15 of 52show all (up to 200)

← intervention of

Abemaciclibsmall molecule

registry intervention “Abemaciclib” (DRUG) mapped ALIAS

—

not mapped

Observed

Radial view

Every edge, grouped by relationship

Paths