Pevonedistat, Azacitidine, Fludarabine Phosphate, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

COMPLETED

Identifier: CI-TRIAL-00088502
Entity page: /trial/NCT03813147 ↗
Edges: 9

Neighbours: 3 cancers4 drugs
Drawn: 7 of 7 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Pevonedistat, Azacitidine, Fludarabine Phosphate, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome condition of …CONDITION_OFderived5 of 5
← condition of	Acute Myeloid Leukemia registry condition “Recurrent Acute Myeloid Leukemia” mapped CURATED_BROADER	—	—	Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →
← condition of	Acute Myeloid Leukemia registry condition “Refractory Acute Myeloid Leukemia” mapped CURATED_BROADER

Pevonedistat, Azacitidine, Fludarabine Phosphate, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome intervention of …INTERVENTION_OFderived4 of 4
← intervention of	Azacitidinesmall molecule registry intervention “Azacitidine” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Cytarabinesmall molecule registry intervention “Cytarabine” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Fludarabinesmall molecule registry intervention “Fludarabine Phosphate” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Methotrexatesmall molecule registry intervention “Methotrexate” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Pevonedistat, Azacitidine, Fludarabine Phosphate, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome intervention of …INTERVENTION_OFderived4 of 4

← intervention of

Azacitidinesmall molecule

registry intervention “Azacitidine” (DRUG) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Cytarabinesmall molecule

registry intervention “Cytarabine” (DRUG) mapped ALIAS

—