Targeted Treatment for ALK Positive Patients Who Have Previously Been Treated for Non-squamous Non-small Cell Lung Cancer

TERMINATED

Identifier: CI-TRIAL-00109281
Entity page: /trial/NCT03737994 ↗
Edges: 13

Neighbours: 2 cancers9 drugs
Drawn: 11 of 11 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Targeted Treatment for ALK Positive Patients Who Have Previously Been Treated for Non-squamous Non-small Cell Lung Cancer condition of …CONDITION_OFderived4 of 4
← condition of	Lung Non-Squamous Non-Small Cell Carcinoma registry condition “Lung Non-Squamous Non-Small Cell Carcinoma” mapped ONTOLOGY_EXACT	—	—	Lung Non-Squamous Non-Small Cell Carcinoma	1	Observed	clinicaltrials	graph →
← condition of	Malignant Lung Neoplasm registry condition “Stage IVA Lung Cancer AJCC v8” mapped CURATED_BROADER

Targeted Treatment for ALK Positive Patients Who Have Previously Been Treated for Non-squamous Non-small Cell Lung Cancer intervention of …INTERVENTION_OFderived9 of 9
← intervention of	Alectinibsmall molecule registry intervention “Alectinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Brigatinibsmall molecule registry intervention “Brigatinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Carboplatinsmall molecule registry intervention “Carboplatin” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Ceritinibsmall molecule registry intervention “Ceritinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Cisplatinsmall molecule registry intervention “Cisplatin” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Crizotinibsmall molecule registry intervention “Crizotinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Ensartinibsmall molecule registry intervention “Ensartinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Lorlatinibsmall molecule registry intervention “Lorlatinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Pemetrexedsmall molecule registry intervention “Pemetrexed” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Targeted Treatment for ALK Positive Patients Who Have Previously Been Treated for Non-squamous Non-small Cell Lung Cancer intervention of …INTERVENTION_OFderived9 of 9

← intervention of

Alectinibsmall molecule

registry intervention “Alectinib” (DRUG) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Brigatinibsmall molecule

registry intervention “Brigatinib” (DRUG) mapped ALIAS

—