Knowledge graph · Trial
(PATHFINDER) Study to Evaluate Efficacy and Safety of Avapritinib (BLU-285), A Selective KIT Mutation-targeted Tyrosine Kinase Inhibitor, in Patients With Advanced Systemic Mastocytosis
COMPLETED
- Identifier
- CI-TRIAL-00109435
- Entity page
- /trial/NCT03580655 ↗
- Edges
- 5
- Neighbours
- 4 cancers1 drugs
- Drawn
- 5 of 5 neighbours (cap 60); table lists every fetched edge
Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.
Most connectedLung Non-Small Cell Carcinoma 3,149Malignant Colorectal Neoplasm 1,866ABL1 298EGFR 276Imatinib 450Dasatinib 321
Neighbourhood
Radial view
Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.
Edges
Every edge, grouped by relationship
Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.
| Relationship | Neighbour | Direction | Evidence level | Cancer context | Support | Claim | Source | Expand |
|---|---|---|---|---|---|---|---|---|
| (PATHFINDER) Study to Evaluate Efficacy and Safety of Avapritinib (BLU-285), A Selective KIT Mutation-targeted Tyrosine Kinase Inhibitor, in Patients With Advanced Systemic Mastocytosis condition of …CONDITION_OFderived4 of 4 | ||||||||
| ← condition of | Aggressive Systemic Mastocytosis registry condition “Aggressive Systemic Mastocytosis” mapped ONTOLOGY_EXACT | — | — | Aggressive Systemic Mastocytosis | 1 | Observed | clinicaltrials | graph → |
| ← condition of | Malignant Mastocytosis registry condition “Advanced Systemic Mastocytosis” mapped CURATED_BROADER | |||||||