Venetoclax, Ponatinib, and Dexamethasone in Participants With Philadelphia Chromosome or BCR-ABL Positive Relapsed or Refractory Acute Lymphoblastic Leukemia or Chronic Myelogenous Leukemia

TERMINATED

Identifier: CI-TRIAL-00089460
Entity page: /trial/NCT03576547 ↗
Edges: 9

Neighbours: 3 cancers4 drugs
Drawn: 7 of 7 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Venetoclax, Ponatinib, and Dexamethasone in Participants With Philadelphia Chromosome or BCR-ABL Positive Relapsed or Refractory Acute Lymphoblastic Leukemia or Chronic Myelogenous Leukemia condition of …CONDITION_OFderived5 of 5
← condition of	Acute Lymphoblastic Leukemia registry condition “Recurrent Acute Lymphoblastic Leukemia” mapped CURATED_BROADER	—	—	Acute Lymphoblastic Leukemia	1	Observed	clinicaltrials	graph →
← condition of	Acute Lymphoblastic Leukemia registry condition “Refractory Acute Lymphoblastic Leukemia” mapped CURATED_BROADER

Venetoclax, Ponatinib, and Dexamethasone in Participants With Philadelphia Chromosome or BCR-ABL Positive Relapsed or Refractory Acute Lymphoblastic Leukemia or Chronic Myelogenous Leukemia intervention of …INTERVENTION_OFderived4 of 4
← intervention of	Dexamethasonesmall molecule registry intervention “Dexamethasone” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Ponatinibsmall molecule registry intervention “Ponatinib Hydrochloride” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Rituximabmonoclonal antibody registry intervention “Rituximab” (BIOLOGICAL) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Venetoclaxsmall molecule registry intervention “Venetoclax” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Venetoclax, Ponatinib, and Dexamethasone in Participants With Philadelphia Chromosome or BCR-ABL Positive Relapsed or Refractory Acute Lymphoblastic Leukemia or Chronic Myelogenous Leukemia intervention of …INTERVENTION_OFderived4 of 4

← intervention of

Dexamethasonesmall molecule

registry intervention “Dexamethasone” (DRUG) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Ponatinibsmall molecule

registry intervention “Ponatinib Hydrochloride” (DRUG) mapped ALIAS

—