An Investigational Immuno-therapy Study Of Nivolumab In Combination With Trametinib With Or Without Ipilimumab In Participants With Previously Treated Cancer of the Colon or Rectum That Has Spread

COMPLETED

Identifier: CI-TRIAL-00098334
Entity page: /trial/NCT03377361 ↗
Edges: 8

Neighbours: 3 cancers4 drugs
Drawn: 7 of 7 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
An Investigational Immuno-therapy Study Of Nivolumab In Combination With Trametinib With Or Without Ipilimumab In Participants With Previously Treated Cancer of the Colon or Rectum That Has Spread condition of …CONDITION_OFderived4 of 4
← condition of	Colorectal Carcinoma registry condition “Colorectal Carcinoma” mapped ONTOLOGY_EXACT	—	—	Colorectal Carcinoma	1	Observed	clinicaltrials	graph →
← condition of	Colorectal Neoplasm registry condition “Colorectal Neoplasm” mapped ONTOLOGY_EXACT

An Investigational Immuno-therapy Study Of Nivolumab In Combination With Trametinib With Or Without Ipilimumab In Participants With Previously Treated Cancer of the Colon or Rectum That Has Spread intervention of …INTERVENTION_OFderived4 of 4
← intervention of	Ipilimumabmonoclonal antibody registry intervention “Ipilimumab” (BIOLOGICAL) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Nivolumabmonoclonal antibody registry intervention “Nivolumab” (BIOLOGICAL) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Regorafenibsmall molecule registry intervention “Regorafenib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Trametinibsmall molecule registry intervention “Trametinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

An Investigational Immuno-therapy Study Of Nivolumab In Combination With Trametinib With Or Without Ipilimumab In Participants With Previously Treated Cancer of the Colon or Rectum That Has Spread intervention of …INTERVENTION_OFderived4 of 4

← intervention of

Ipilimumabmonoclonal antibody

registry intervention “Ipilimumab” (BIOLOGICAL) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Nivolumabmonoclonal antibody

registry intervention “Nivolumab” (BIOLOGICAL) mapped ALIAS

—