Nivolumab With Trametinib and Dabrafenib, or Encorafenib and Binimetinib in Treating Patients With BRAF Mutated Metastatic or Unresectable Stage III-IV Melanoma

ACTIVE NOT RECRUITING

Identifier: CI-TRIAL-00114468
Entity page: /trial/NCT02910700 ↗
Edges: 11

Neighbours: 2 cancers5 drugs
Drawn: 7 of 7 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Nivolumab With Trametinib and Dabrafenib, or Encorafenib and Binimetinib in Treating Patients With BRAF Mutated Metastatic or Unresectable Stage III-IV Melanoma condition of …CONDITION_OFderived6 of 6
← condition of	Cutaneous Melanoma registry condition “Stage IIIA Cutaneous Melanoma AJCC v7” mapped CURATED_BROADER	—	—	Cutaneous Melanoma	1	Observed	clinicaltrials	graph →
← condition of	Cutaneous Melanoma registry condition “Stage IIIB Cutaneous Melanoma AJCC v7” mapped CURATED_BROADER

Nivolumab With Trametinib and Dabrafenib, or Encorafenib and Binimetinib in Treating Patients With BRAF Mutated Metastatic or Unresectable Stage III-IV Melanoma intervention of …INTERVENTION_OFderived5 of 5
← intervention of	Binimetinibsmall molecule registry intervention “Binimetinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Dabrafenibsmall molecule registry intervention “Dabrafenib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Encorafenibsmall molecule registry intervention “Encorafenib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Nivolumabmonoclonal antibody registry intervention “Nivolumab” (BIOLOGICAL) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Trametinibsmall molecule registry intervention “Trametinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Nivolumab With Trametinib and Dabrafenib, or Encorafenib and Binimetinib in Treating Patients With BRAF Mutated Metastatic or Unresectable Stage III-IV Melanoma intervention of …INTERVENTION_OFderived5 of 5

← intervention of

Binimetinibsmall molecule

registry intervention “Binimetinib” (DRUG) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Dabrafenibsmall molecule

registry intervention “Dabrafenib” (DRUG) mapped ALIAS

—