Study Assessing Activity of Molecularly Matched Targeted Therapies in Select Tumor Types Based on Genomic Alterations

COMPLETED

Identifier: CI-TRIAL-00071984
Entity page: /trial/NCT02795156 ↗
Edges: 5

Neighbours: 2 cancers3 drugs
Drawn: 5 of 5 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Study Assessing Activity of Molecularly Matched Targeted Therapies in Select Tumor Types Based on Genomic Alterations condition of …CONDITION_OFderived2 of 2
← condition of	Lung Non-Small Cell Carcinoma registry condition “Non-small Cell Lung Carcinoma” mapped ALIAS	—	—	Lung Non-Small Cell Carcinoma	1	Observed	clinicaltrials	graph →
← condition of	Urothelial Carcinoma registry condition “Urothelial Carcinoma” mapped ONTOLOGY_EXACT

Study Assessing Activity of Molecularly Matched Targeted Therapies in Select Tumor Types Based on Genomic Alterations intervention of …INTERVENTION_OFderived3 of 3
← intervention of	Afatinibsmall molecule registry intervention “Afatinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Cabozantinibsmall molecule registry intervention “Cabozantinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Regorafenibsmall molecule registry intervention “Regorafenib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Study Assessing Activity of Molecularly Matched Targeted Therapies in Select Tumor Types Based on Genomic Alterations intervention of …INTERVENTION_OFderived3 of 3

← intervention of

Afatinibsmall molecule

registry intervention “Afatinib” (DRUG) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Cabozantinibsmall molecule

registry intervention “Cabozantinib” (DRUG) mapped ALIAS

—