National Lung Matrix Trial: Multi-drug Phase II Trial in Non-Small Cell Lung Cancer

COMPLETED

Identifier: CI-TRIAL-00109671
Entity page: /trial/NCT02664935 ↗
Edges: 12

Neighbours: 3 cancers9 drugs
Drawn: 12 of 12 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
National Lung Matrix Trial: Multi-drug Phase II Trial in Non-Small Cell Lung Cancer condition of …CONDITION_OFderived3 of 3
← condition of	Adenocarcinoma registry condition “Adenocarcinoma” mapped ONTOLOGY_EXACT	—	—	Adenocarcinoma	1	Observed	clinicaltrials	graph →
← condition of	Lung Non-Small Cell Carcinoma registry condition “Non-Small Cell Lung Cancer” mapped ALIAS	—	—

National Lung Matrix Trial: Multi-drug Phase II Trial in Non-Small Cell Lung Cancer intervention of …INTERVENTION_OFderived9 of 9
← intervention of	Capivasertibsmall molecule registry intervention “AZD5363” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Crizotinibsmall molecule registry intervention “Crizotinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Docetaxelsmall molecule registry intervention “Docetaxel” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Durvalumabmonoclonal antibody registry intervention “Durvalumab” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Fexagratinibsmall molecule registry intervention “AZD4547” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Osimertinibsmall molecule registry intervention “Osimertinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Palbociclibsmall molecule registry intervention “Palbociclib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Selumetinibsmall molecule registry intervention “Selumetinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Vistusertibsmall molecule registry intervention “Vistusertib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

National Lung Matrix Trial: Multi-drug Phase II Trial in Non-Small Cell Lung Cancer intervention of …INTERVENTION_OFderived9 of 9

← intervention of

Capivasertibsmall molecule

registry intervention “AZD5363” (DRUG) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Crizotinibsmall molecule

registry intervention “Crizotinib” (DRUG) mapped ALIAS