Genomics-Based Target Therapy for Children With Relapsed or Refractory Malignancy

UNKNOWN

Identifier: CI-TRIAL-00044141
Entity page: /trial/NCT02638428 ↗
Edges: 21

Neighbours: 2 cancers15 drugs
Drawn: 17 of 17 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Genomics-Based Target Therapy for Children With Relapsed or Refractory Malignancy condition of …CONDITION_OFderived4 of 4
← condition of	Childhood Acute Myeloid Leukemia registry condition “Refractory Pediatric AML” mapped CURATED_BROADER	—	—	Childhood Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →
← condition of	Childhood Acute Myeloid Leukemia registry condition “Relapsed Pediatric AML” mapped CURATED_BROADER

Genomics-Based Target Therapy for Children With Relapsed or Refractory Malignancy intervention of …INTERVENTION_OFderived15 of 17show all (up to 200)
← intervention of	Axitinibsmall molecule registry intervention “Axitinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Carboplatinsmall molecule registry intervention “Carboplatin” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Crizotinibsmall molecule registry intervention “Crizotinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Cytarabinesmall molecule registry intervention “Cytarabine” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Dasatinibsmall molecule registry intervention “Dasatinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Erlotinibsmall molecule registry intervention “Erlotinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Etoposidesmall molecule registry intervention “Etoposide” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Everolimussmall molecule registry intervention “Everolimus” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Fludarabinesmall molecule registry intervention “Fludarabine” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Ifosfamidesmall molecule registry intervention “Ifosfamide” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Imatinibsmall molecule registry intervention “Imatinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Pazopanibsmall molecule registry intervention “Pazopanib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Ruxolitinibsmall molecule registry intervention “Ruxolitinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Sorafenibsmall molecule registry intervention “Sorafenib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Trastuzumabmonoclonal antibody registry intervention “Trastuzumab” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Genomics-Based Target Therapy for Children With Relapsed or Refractory Malignancy intervention of …INTERVENTION_OFderived15 of 17show all (up to 200)

← intervention of

Axitinibsmall molecule

registry intervention “Axitinib” (DRUG) mapped ALIAS

—

not mapped

Observed

Radial view

Every edge, grouped by relationship

Paths