Study to Evaluate Ibrutinib Combination Therapy in Patients With Selected Gastrointestinal and Genitourinary Tumors

COMPLETED

Identifier: CI-TRIAL-00071506
Entity page: /trial/NCT02599324 ↗
Edges: 10

Neighbours: 4 cancers6 drugs
Drawn: 10 of 10 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Study to Evaluate Ibrutinib Combination Therapy in Patients With Selected Gastrointestinal and Genitourinary Tumors condition of …CONDITION_OFderived4 of 4
← condition of	Colorectal Adenocarcinoma registry condition “Metastatic Colorectal Adenocarcinoma” mapped CURATED_BROADER	—	—	Colorectal Adenocarcinoma	1	Observed	clinicaltrials	graph →
← condition of	Gastric Adenocarcinoma registry condition “Advanced Gastric Adenocarcinoma” mapped CURATED_BROADER

Study to Evaluate Ibrutinib Combination Therapy in Patients With Selected Gastrointestinal and Genitourinary Tumors intervention of …INTERVENTION_OFderived6 of 6
← intervention of	Cetuximabmonoclonal antibody registry intervention “cetuximab” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Docetaxelsmall molecule registry intervention “docetaxel” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Everolimussmall molecule registry intervention “everolimus” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Ibrutinibsmall molecule registry intervention “ibrutinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Paclitaxelsmall molecule registry intervention “paclitaxel” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Pembrolizumabmonoclonal antibody registry intervention “pembrolizumab” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Study to Evaluate Ibrutinib Combination Therapy in Patients With Selected Gastrointestinal and Genitourinary Tumors intervention of …INTERVENTION_OFderived6 of 6

← intervention of

Cetuximabmonoclonal antibody

registry intervention “cetuximab” (DRUG) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Docetaxelsmall molecule

registry intervention “docetaxel” (DRUG) mapped ALIAS

—