Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors

COMPLETED

Identifier: CI-TRIAL-00052874
Entity page: /trial/NCT01217437 ↗
Edges: 9

Neighbours: 5 cancers3 drugs
Drawn: 8 of 8 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors condition of …CONDITION_OFderived6 of 6
← condition of	Central Nervous System Neoplasm registry condition “Central Nervous System Neoplasm” mapped ONTOLOGY_EXACT	—	—	Central Nervous System Neoplasm	1	Observed	clinicaltrials	graph →
← condition of	Medulloblastoma registry condition “Recurrent Medulloblastoma” mapped CURATED_BROADER

Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors intervention of …INTERVENTION_OFderived3 of 3
← intervention of	Bevacizumabmonoclonal antibody registry intervention “Bevacizumab” (BIOLOGICAL) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Irinotecansmall molecule registry intervention “Irinotecan Hydrochloride” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Temozolomidesmall molecule registry intervention “Temozolomide” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors intervention of …INTERVENTION_OFderived3 of 3

← intervention of

Bevacizumabmonoclonal antibody

registry intervention “Bevacizumab” (BIOLOGICAL) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Irinotecansmall molecule

registry intervention “Irinotecan Hydrochloride” (DRUG) mapped ALIAS

—