Knowledge graph · Trial
A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors
COMPLETED
- Identifier
- CI-TRIAL-00042104
- Entity page
- /trial/NCT00994071 ↗
- Edges
- 7
- Neighbours
- 5 cancers2 drugs
- Drawn
- 7 of 7 neighbours (cap 60); table lists every fetched edge
Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.
Most connectedLung Non-Small Cell Carcinoma 3,147Malignant Colorectal Neoplasm 1,866ABL1 298EGFR 276Imatinib 450Dasatinib 321
Neighbourhood
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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.
Edges
Every edge, grouped by relationship
Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.
| Relationship | Neighbour | Direction | Evidence level | Cancer context | Support | Claim | Source | Expand |
|---|---|---|---|---|---|---|---|---|
| A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors condition of …CONDITION_OFderived5 of 5 | ||||||||
| ← condition of | Astrocytoma registry condition “Astrocytoma” mapped CURATED_BROADER | — | — | Astrocytoma | 1 | Observed | clinicaltrials | graph → |
| ← condition of | Brain Neoplasm registry condition “Pontine Glioma” mapped PROBABILISTIC | — | — | |||||