Knowledge graph · Trial
A Phase I, Open-Label, Multi-center Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD6244 (ARRY-142886)
COMPLETED
- Identifier
- CI-TRIAL-00112738
- Entity page
- /trial/NCT00600496 ↗
- Edges
- 12
- Neighbours
- 7 cancers5 drugs
- Drawn
- 12 of 12 neighbours (cap 60); table lists every fetched edge
Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.
Most connectedLung Non-Small Cell Carcinoma 3,147Malignant Colorectal Neoplasm 1,866ABL1 298EGFR 276Imatinib 450Dasatinib 321
Neighbourhood
Radial view
Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.
Edges
Every edge, grouped by relationship
Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.
| Relationship | Neighbour | Direction | Evidence level | Cancer context | Support | Claim | Source | Expand |
|---|---|---|---|---|---|---|---|---|
| A Phase I, Open-Label, Multi-center Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD6244 (ARRY-142886) condition of …CONDITION_OFderived7 of 7 | ||||||||
| ← condition of | Breast Neoplasm registry condition “Breast Neoplasms” mapped ONTOLOGY_EXACT | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| ← condition of | Colon Neoplasm registry condition “Colon Neoplasms” mapped ONTOLOGY_EXACT | — | — | |||||