Knowledge graph · Gene
TRHDE
thyrotropin releasing hormone degrading enzyme
- Identifier
- CI-GENE-00036583
- Entity page
- /gene/TRHDE ↗
- Edges
- 2
- Neighbours
- 2 cancers
- Drawn
- 2 of 2 neighbours (cap 60); table lists every fetched edge
Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.
Most connectedLung Non-Small Cell Carcinoma 3,147Malignant Colorectal Neoplasm 1,866ABL1 298EGFR 276Imatinib 450Dasatinib 321
Neighbourhood
Radial view
Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.
Edges
Every edge, grouped by relationship
Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.
| Relationship | Neighbour | Direction | Evidence level | Cancer context | Support | Claim | Source | Expand |
|---|---|---|---|---|---|---|---|---|
| TRHDE altered in cohorts of …ALTERED_INderived2 of 2 | ||||||||
| → altered in cohorts of | Cutaneous Melanoma 70 / 469 cases (15 %) · ssm · skcm_tcga_gdc · largest of 3 cohorts | — | — | Cutaneous Melanoma | 3 | Observed | cbioportal | graph → |
| → altered in cohorts of | Lung Squamous Cell Carcinoma 45 / 484 cases (9.3 %) · ssm · lusc_tcga_pan_can_atlas_2018 · largest of 2 cohorts | — | ||||||