KLLN

killin, p53 regulated DNA replication inhibitor

Identifier: CI-GENE-00007095
Entity page: /gene/KLLN ↗
Edges: 8

Neighbours: 3 cancers5 variants
Drawn: 8 of 8 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
KLLN associated with …ASSOCIATED_WITH2 of 2
→ associated with	Renal Cell Carcinomasubtype	supports	B	Renal Cell Carcinoma	1	Curated	civic	graph →
→ associated with	Malignant Breast Neoplasmcancer_family	supports	B

KLLN has variant …HAS_VARIANTderived5 of 5
→ has variant	PROMOTER METHYLATIONepigenetic 2 accepted CIViC evidence items	—	—	Malignant Breast Neoplasm,Renal Cell Carcinoma	2	Curated	civic	graph →
→ has variant	NM_001126049.2(KLLN):c.184C>G (p.Arg62Gly)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_001126049.2(KLLN):c.226T>C (p.Phe76Leu)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_001126049.2(KLLN):c.316C>A (p.Pro106Thr)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_001126049.2(KLLN):c.526C>A (p.Pro176Thr)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →

KLLN has variant …HAS_VARIANTderived5 of 5

→ has variant

PROMOTER METHYLATIONepigenetic

2 accepted CIViC evidence items

—

Malignant Breast Neoplasm,Renal Cell Carcinoma

Curated

civic

graph →

→ has variant

NM_001126049.2(KLLN):c.184C>G (p.Arg62Gly)SNV

no accepted CIViC evidence item (variant record only)