H3-3A

H3.3 histone A

Identifier: CI-GENE-00004001
Entity page: /gene/H3-3A ↗
Edges: 17

Neighbours: 6 cancers10 variants
Drawn: 16 of 16 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
H3-3A associated with …ASSOCIATED_WITH6 of 6
→ associated with	Diffuse Midline Glioma, H3 K27-Alteredmolecular_subtype	supports	A	Diffuse Midline Glioma, H3 K27-Altered	1	Curated	civic	graph →
→ associated with	Giant Cell Tumor of Bonesubtype 3 source records aggregated

H3-3A has variant …HAS_VARIANTderived10 of 10
→ has variant	K28MSNV 6 accepted CIViC evidence items	—	—	Glioma,Brain Glioblastoma,Diffuse Midline Glioma, H3 K27-Altered	6	Curated	civic	graph →
→ has variant	G35WSNV 3 accepted CIViC evidence items	—	—	Giant Cell Tumor of Bone	3	Curated	civic	graph →
→ has variant	G35RSNV 1 accepted CIViC evidence items	—	—	not mapped	1	Curated	civic	graph →
→ has variant	MUTATIONother 1 accepted CIViC evidence items	—	—	Childhood Low Grade Glioma	1	Curated	civic	graph →
→ has variant	G35 no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	G35VSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	K28 no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	K28ISNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	K28RSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_002107.7(H3-3A):c.103_104delinsTT (p.Gly35Leu)indel no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →

H3-3A has variant …HAS_VARIANTderived10 of 10

→ has variant

K28MSNV

6 accepted CIViC evidence items

—

Glioma,Brain Glioblastoma,Diffuse Midline Glioma, H3 K27-Altered

Curated

civic

graph →

→ has variant

G35WSNV

3 accepted CIViC evidence items