FOS

Fos proto-oncogene, AP-1 transcription factor subunit

Identifier: CI-GENE-00002120
Entity page: /gene/FOS ↗
Edges: 7

Neighbours: 3 cancers4 variants
Drawn: 7 of 7 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
FOS associated with …ASSOCIATED_WITH3 of 3
→ associated with	Osteoblastomasubtype 2 source records aggregated	supports	B	Osteoblastoma	2	Curated	civic	graph →
→ associated with	Colon Adenocarcinomasubtype	supports	C

FOS has variant …HAS_VARIANTderived4 of 4
→ has variant	Rearrangementstructural 2 accepted CIViC evidence items	—	—	Osteoblastoma	2	Curated	civic	graph →
→ has variant	Fusionfusion 1 accepted CIViC evidence items	—	—	Bone Epithelioid Hemangioma	1	Curated	civic	graph →
→ has variant	Overexpressionexpression 1 accepted CIViC evidence items	—	—	Colon Adenocarcinoma	1	Curated	civic	graph →
→ has variant	NM_005252.4(FOS):c.189G>A (p.Thr63=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →

FOS has variant …HAS_VARIANTderived4 of 4

→ has variant

Rearrangementstructural

2 accepted CIViC evidence items

—

Osteoblastoma

Curated

civic

graph →

→ has variant

Fusionfusion

1 accepted CIViC evidence items