Knowledge graph · Gene
ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif 12
- Identifier
- CI-GENE-00000456
- Entity page
- /gene/ADAMTS12 ↗
- Edges
- 5
- Neighbours
- 5 cancers
- Drawn
- 5 of 5 neighbours (cap 60); table lists every fetched edge
Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.
Most connectedLung Non-Small Cell Carcinoma 3,149Malignant Colorectal Neoplasm 1,866ABL1 298EGFR 276Imatinib 450Dasatinib 321
Neighbourhood
Radial view
Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.
Edges
Every edge, grouped by relationship
Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.
| Relationship | Neighbour | Direction | Evidence level | Cancer context | Support | Claim | Source | Expand |
|---|---|---|---|---|---|---|---|---|
| ADAMTS12 altered in cohorts of …ALTERED_INderived5 of 5 | ||||||||
| → altered in cohorts of | Lung Adenocarcinoma 99 / 566 cases (17 %) · ssm · luad_tcga_pan_can_atlas_2018 · largest of 7 cohorts | — | — | Lung Adenocarcinoma | 7 | Observed | cbioportal | graph → |
| → altered in cohorts of | Lung Non-Small Cell Carcinoma 196 / 1,144 cases (17 %) · ssm · nsclc_tcga_broad_2016 | — | ||||||