FOLFOX-6 Regimen

Identifier: CI-DRUG-00000242
Entity page: /drug/folfox-6-regimen ↗
Edges: 16

Neighbours: 7 cancers9 trials
Drawn: 16 of 16 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
FOLFOX-6 Regimen investigated in trials for …INVESTIGATED_IN_TRIALSderived7 of 7
→ investigated in trials for	Malignant Rectal Neoplasm 3 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Rectal Neoplasm	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Colon Neoplasm 2 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—

FOLFOX-6 Regimen studied in …STUDIED_INderived9 of 9
→ studied in	NCT07500298Phase 1 · recruiting Phase 1 Study Of SAR445877 In Combination With FOLFOX6 And Bevacizumab As First-Line Treatment For Microsatellite Stable Metastatic Colorectal Cancer · 9 trials list this drug (1 active)	—	—	Malignant Colorectal Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT02243358Phase 2 · completed Phase II Study of Chemo-Radiotherapy in Patients With Resectable and Borderline Resectable Pancreatic Cancer · 9 trials list this drug (1 active)	—	—	Pancreatic Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT02017704Phase 2 · completed Chemoradiation or Brachytherapy for Rectal Cancer · 9 trials list this drug (1 active)	—	—	Malignant Rectal Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT01420874Phase 1 · completed Anti-CD3 x Anti-Erbitux® Armed Activated T Cells (Phase Ib) for Gastrointestinal (GI Cancer) · 9 trials list this drug (1 active)	—	—	Malignant Pancreatic Neoplasm,Pancreatic Neoplasm,Malignant Colorectal Neoplasm+2	1	Observed	clinicaltrials	graph →
→ studied in	NCT05590117early Phase 1 · unknown Protective Effect of Pentoxifylline Against Chemotherapy Induced Toxicities in Patients With Colorectal Cancer · 9 trials list this drug (1 active)	—	—	not mapped	1	Observed	clinicaltrials	graph →
→ studied in	NCT01363843Phase 2 · completed Complete Neoadjuvant Treatment for REctal Cancer (CONTRE) · 9 trials list this drug (1 active)	—	—	Malignant Colon Neoplasm,Malignant Rectal Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT01749956Phase 2 · completed 5-FU, Aflibercept, and Radiation (RT) for Preoperative and Postoperative Patients With Stage II/III Rectal Cancer · 9 trials list this drug (1 active)	—	—	Malignant Rectal Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT01508000Phase 2 · terminated Efficacy of FOLFOX Alone, FOLFOX Plus Bevacizumab and FOLFOX Plus Panitumumab in Patients With Resectable Liver Metastases · 9 trials list this drug (1 active)	—	—	not mapped	1	Observed	clinicaltrials	graph →
→ studied in	NCT01605305Phase 2 · completed Study on FOLFOX6 as First-line Therapy to Treat Recurrent or Metastatic Esophageal Cancer · 9 trials list this drug (1 active)	—	—	Esophageal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →

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