Primary Central Nervous System B-Cell Non-Hodgkin Lymphoma

hematologic malignancy

Identifier: CI-CAN-00003728
Entity page: /cancer/primary-central-nervous-system-b-cell-non-hodgkin-lymphoma ↗
Edges: 14

Neighbours: 10 drugs4 trials
Drawn: 14 of 14 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Primary Central Nervous System B-Cell Non-Hodgkin Lymphoma investigated in trials for …INVESTIGATED_IN_TRIALSderived10 of 10
→ investigated in trials for	Lenalidomidesmall molecule 2 trials (2 active) · roll-up of the cancer and its descendants	—	—	Primary Central Nervous System B-Cell Non-Hodgkin Lymphoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Nivolumabmonoclonal antibody

Primary Central Nervous System B-Cell Non-Hodgkin Lymphoma studied in …STUDIED_INderived4 of 4
→ studied in	NCT04609046Phase 1 · active not recruiting Testing the Addition of Lenalidomide and Nivolumab to the Usual Treatment for Primary CNS Lymphoma · condition mapped ONTOLOGY_EXACT · 4 trials mapped (3 active)	—	—	Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System	1	Observed	clinicaltrials	graph →
→ studied in	NCT03038672Phase 2 · active not recruiting Nivolumab With or Without Varlilumab in Treating Patients With Relapsed or Refractory Aggressive B-cell Lymphomas · condition mapped ONTOLOGY_EXACT · 4 trials mapped (3 active)	—	—	Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System	1	Observed	clinicaltrials	graph →
→ studied in	NCT05211336Phase 1 · active not recruiting Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (VIPOR) for Diffuse Large B-cell Lymphoma Involving the Central Nervous System · condition mapped ONTOLOGY_EXACT · 4 trials mapped (3 active)	—	—	Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System	1	Observed	clinicaltrials	graph →
→ studied in	NCT01722305Phase 1 · completed Pomalidomide and Dexamethasone in Treating Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma or Newly Diagnosed or Relapsed or Refractory Intraocular Lymphoma · condition mapped ONTOLOGY_EXACT · 4 trials mapped (3 active)	—	—	Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System	1	Observed	clinicaltrials	graph →

Primary Central Nervous System B-Cell Non-Hodgkin Lymphoma studied in …STUDIED_INderived4 of 4

→ studied in

NCT04609046Phase 1 · active not recruiting

Testing the Addition of Lenalidomide and Nivolumab to the Usual Treatment for Primary CNS Lymphoma · condition mapped ONTOLOGY_EXACT · 4 trials mapped (3 active)

—

Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System

Observed

clinicaltrials

graph →

→ studied in

NCT03038672Phase 2 · active not recruiting

Nivolumab With or Without Varlilumab in Treating Patients With Relapsed or Refractory Aggressive B-cell Lymphomas · condition mapped ONTOLOGY_EXACT · 4 trials mapped (3 active)

—

Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System

Observed

clinicaltrials

graph →

→ studied in

NCT05211336Phase 1 · active not recruiting

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (VIPOR) for Diffuse Large B-cell Lymphoma Involving the Central Nervous System · condition mapped ONTOLOGY_EXACT · 4 trials mapped (3 active)

—

Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System

Observed

clinicaltrials

graph →

→ studied in

NCT01722305Phase 1 · completed

Pomalidomide and Dexamethasone in Treating Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma or Newly Diagnosed or Relapsed or Refractory Intraocular Lymphoma · condition mapped ONTOLOGY_EXACT · 4 trials mapped (3 active)

—

Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System

Observed

clinicaltrials

graph →

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