MGMT-Methylated Glioblastoma

subtype

Identifier: CI-CAN-00006023
Entity page: /cancer/mgmt-methylated-glioblastoma ↗
Edges: 14

Neighbours: 6 drugs8 trials
Drawn: 14 of 14 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
MGMT-Methylated Glioblastoma investigated in trials for …INVESTIGATED_IN_TRIALSderived6 of 6
→ investigated in trials for	Temozolomidesmall molecule 6 trials (5 active) · roll-up of the cancer and its descendants	—	—	MGMT-Methylated Glioblastoma	6	Observed	clinicaltrials	graph →
→ investigated in trials for	Lenvatinibsmall molecule 1 trials (1 active) · roll-up of the cancer and its descendants

MGMT-Methylated Glioblastoma studied in …STUDIED_INderived8 of 8
→ studied in	NCT05432804Phase 1/Phase 2 · recruiting Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment · condition mapped CURATED_BROADER · 8 trials mapped (6 active)	—	—	MGMT-Methylated Glioblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07754734Phase 2 · not yet recruiting STUPP Regimen With or Without Lenvatinib for Newly Diagnosed Glioblastoma With MGMT Promoter Methylation · condition mapped ONTOLOGY_EXACT · 8 trials mapped (6 active)	—	—	MGMT-Methylated Glioblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06991101Phase 2 · recruiting Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma · condition mapped ONTOLOGY_EXACT · 8 trials mapped (6 active)	—	—	MGMT-Methylated Glioblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06649851Phase 2 · recruiting G-CSF After Chemo-radiation in Patients With Glioblastoma · condition mapped ONTOLOGY_EXACT · 8 trials mapped (6 active)	—	—	MGMT-Methylated Glioblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06419946Phase 3 · recruiting Lomustine in Addition to Standard of Care in Patients With MGMT Methylated Glioblastoma · condition mapped ONTOLOGY_EXACT · 8 trials mapped (6 active)	—	—	MGMT-Methylated Glioblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06504381Phase 1/Phase 2 · recruiting DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma · condition mapped ONTOLOGY_EXACT · 8 trials mapped (6 active)	—	—	MGMT-Methylated Glioblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06095375Phase 1 · completed Regorafenib With Temozolomide With or Without RT in MGMT-Methylated, IDH Wild-type GBM Patients · condition mapped ONTOLOGY_EXACT · 8 trials mapped (6 active)	—	—	MGMT-Methylated Glioblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04926168withdrawn 6 Months Adjuvant Temozolomide (TMZ) vs No Adjuvant TMZ in Newly Diagnosed MGMT Methylated Glioblastoma (GBM) · condition mapped ONTOLOGY_EXACT · 8 trials mapped (6 active)	—	—	MGMT-Methylated Glioblastoma	1	Observed	clinicaltrials	graph →

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