HER2-Positive Colorectal Carcinoma — knowledge graph · CancerIndex

Knowledge graph · Cancer

HER2-Positive Colorectal Carcinoma

molecular subtype

Identifier: CI-CAN-00008904
Entity page: /cancer/her2-positive-colorectal-carcinoma ↗
Edges: 10

Neighbours: 4 drugs6 trials
Drawn: 10 of 10 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
HER2-Positive Colorectal Carcinoma investigated in trials for …INVESTIGATED_IN_TRIALSderived4 of 4
→ investigated in trials for	Capecitabinesmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	HER2-Positive Colorectal Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Nivolumabmonoclonal antibody 1 trials (0 active) · roll-up of the cancer and its descendants

HER2-Positive Colorectal Carcinoma studied in …STUDIED_INderived6 of 6
→ studied in	NCT06253871Phase 1 · recruiting A Phase 1/1b Study of IAM1363 in HER2 Cancers · condition mapped ALIAS · 6 trials mapped (3 active)	—	—	HER2-Positive Colorectal Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05514717Phase 1 · terminated A Study of XMT-2056 in Advanced/Recurrent Solid Tumors That Express HER2 · condition mapped ALIAS · 6 trials mapped (3 active)	—	—	HER2-Positive Colorectal Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07384377Phase 3 · not yet recruiting JSKN003 Versus Physician Choiced Treatment in Patients With HER2-positive and Advanced Colorectal Cancer Who Had Failed to Respond to Oxaliplatin, 5-Fu, and Irinotecan · condition mapped ALIAS · 6 trials mapped (3 active)	—	—	HER2-Positive Colorectal Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04278144Phase 1/Phase 2 · terminated A First-in-human Study Using BDC-1001 as a Single Agent and in Combination With Nivolumab in Advanced HER2-Expressing Solid Tumors · condition mapped ALIAS · 6 trials mapped (3 active)	—	—	HER2-Positive Colorectal Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05985707Phase 2 · not yet recruiting KN026 Plus Chemotherapy ± KN-046 in HER2 Positive Colorectal Cancer and Biliary Carcinoma · condition mapped ALIAS · 6 trials mapped (3 active)	—	—	HER2-Positive Colorectal Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05091528Phase 1/Phase 2 · terminated A Safety and Activity Study of SBT6050 in Combination With Other HER2-directed Therapies for HER2-positive Cancers · condition mapped ALIAS · 6 trials mapped (3 active)	—	—	HER2-Positive Colorectal Carcinoma	1	Observed	clinicaltrials	graph →