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Knowledge graph · Cancer

Diffuse Malignant Mesothelioma

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Identifier: CI-CAN-00000810
Entity page: /cancer/diffuse-malignant-mesothelioma ↗
Edges: 36

Neighbours: 17 drugs10 trials
Drawn: 27 of 27 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Diffuse Malignant Mesothelioma investigated in trials for …INVESTIGATED_IN_TRIALSderived17 of 17show fewer
→ investigated in trials for	Cisplatinsmall molecule 6 trials (3 active) · roll-up of the cancer and its descendants	—	—	Diffuse Malignant Mesothelioma	6	Observed	clinicaltrials	graph →
→ investigated in trials for	Pemetrexedsmall molecule

Diffuse Malignant Mesothelioma studied in …STUDIED_INderived10 of 19show all (up to 200)
→ studied in	NCT01064648Phase 1/Phase 2 · active not recruiting Pemetrexed Disodium and Cisplatin With or Without Cediranib Maleate in Treating Patients With Malignant Pleural Mesothelioma · condition mapped ONTOLOGY_EXACT · 19 trials mapped (5 active)	—	—	Epithelioid Mesothelioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05647265Phase 2 · recruiting Testing the Addition of Immunotherapy Before Surgery for Patients With Sarcomatoid Mesothelioma · condition mapped ONTOLOGY_EXACT · 19 trials mapped (5 active)	—	—	Pleural Biphasic Mesothelioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03228537Phase 1 · active not recruiting Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma · condition mapped ONTOLOGY_EXACT · 19 trials mapped (5 active)	—	—	Biphasic Mesothelioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04491942Phase 1 · active not recruiting Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer · condition mapped CURATED_BROADER · 19 trials mapped (5 active)	—	—	Pleural Diffuse Malignant Mesothelioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04158141Phase 3 · terminated Testing the Addition of Targeted Radiation Therapy to Surgery and the Usual Chemotherapy Treatment (Pemetrexed and Cisplatin [or Carboplatin]) for Stage I-IIIA Malignant Pleural Mesothelioma · condition mapped ONTOLOGY_EXACT · 19 trials mapped (5 active)	—	—	Pleural Biphasic Mesothelioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02399371Phase 2 · completed Pembrolizumab in Treating Patients With Malignant Mesothelioma · condition mapped ONTOLOGY_EXACT · 19 trials mapped (5 active)	—	—	Biphasic Mesothelioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07121374Phase 1/Phase 2 · recruiting NEoadjuvant Chemotherapy and Immunotherapy for a Selected Group of Inoperable Pleural Mesothelioma Patients (NECIM): a Feasibility Study · condition mapped ONTOLOGY_EXACT · 19 trials mapped (5 active)	—	—	Pleural Epithelioid Mesothelioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04034238Phase 1 · completed Mesothelin-Targeted Immunotoxin LMB-100 in Combination With Tofacitinib in Persons With Previously Treated Pancreatic Adenocarcinoma, Cholangiocarcinoma and Other Mesothelin Expressing Solid Tumors · condition mapped ONTOLOGY_EXACT · 19 trials mapped (5 active)	—	—	Epithelioid Mesothelioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02672033NA · terminated Accelerated Hypofractionated Radiation Therapy Immediately Before Surgery in Treating Patients With Malignant Pleural Mesothelioma · condition mapped ONTOLOGY_EXACT · 19 trials mapped (5 active)	—	—	Pleural Epithelioid Mesothelioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT00365053Phase 2 · completed PXD101 as Second-Line Therapy in Treating Patients With Malignant Mesothelioma of the Chest That Cannot Be Removed By Surgery · condition mapped ALIAS · 19 trials mapped (5 active)	—	—	Epithelioid Mesothelioma	1	Observed	clinicaltrials	graph →

Diffuse Malignant Mesothelioma studied in …STUDIED_INderived10 of 19show all (up to 200)

→ studied in

NCT01064648Phase 1/Phase 2 · active not recruiting

Pemetrexed Disodium and Cisplatin With or Without Cediranib Maleate in Treating Patients With Malignant Pleural Mesothelioma · condition mapped ONTOLOGY_EXACT · 19 trials mapped (5 active)

—

Epithelioid Mesothelioma

Observed

clinicaltrials

graph →

→ studied in

NCT05647265Phase 2 · recruiting

Testing the Addition of Immunotherapy Before Surgery for Patients With Sarcomatoid Mesothelioma · condition mapped ONTOLOGY_EXACT · 19 trials mapped (5 active)

—

Pleural Biphasic Mesothelioma

Observed

clinicaltrials

graph →

→ studied in

NCT03228537Phase 1 · active not recruiting

Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma · condition mapped ONTOLOGY_EXACT · 19 trials mapped (5 active)

—

Biphasic Mesothelioma

Observed

clinicaltrials

graph →

→ studied in

NCT04491942Phase 1 · active not recruiting

Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer · condition mapped CURATED_BROADER · 19 trials mapped (5 active)

—

Pleural Diffuse Malignant Mesothelioma

Observed

clinicaltrials

graph →

→ studied in

NCT04158141Phase 3 · terminated

Testing the Addition of Targeted Radiation Therapy to Surgery and the Usual Chemotherapy Treatment (Pemetrexed and Cisplatin [or Carboplatin]) for Stage I-IIIA Malignant Pleural Mesothelioma · condition mapped ONTOLOGY_EXACT · 19 trials mapped (5 active)

—

Pleural Biphasic Mesothelioma

Observed

clinicaltrials

graph →

→ studied in

NCT02399371Phase 2 · completed

Pembrolizumab in Treating Patients With Malignant Mesothelioma · condition mapped ONTOLOGY_EXACT · 19 trials mapped (5 active)

—

Biphasic Mesothelioma

Observed

clinicaltrials

graph →

→ studied in

NCT07121374Phase 1/Phase 2 · recruiting

NEoadjuvant Chemotherapy and Immunotherapy for a Selected Group of Inoperable Pleural Mesothelioma Patients (NECIM): a Feasibility Study · condition mapped ONTOLOGY_EXACT · 19 trials mapped (5 active)

—

Pleural Epithelioid Mesothelioma

Observed

clinicaltrials

graph →

→ studied in

NCT04034238Phase 1 · completed

Mesothelin-Targeted Immunotoxin LMB-100 in Combination With Tofacitinib in Persons With Previously Treated Pancreatic Adenocarcinoma, Cholangiocarcinoma and Other Mesothelin Expressing Solid Tumors · condition mapped ONTOLOGY_EXACT · 19 trials mapped (5 active)

—

Epithelioid Mesothelioma

Observed

clinicaltrials

graph →

→ studied in

NCT02672033NA · terminated

Accelerated Hypofractionated Radiation Therapy Immediately Before Surgery in Treating Patients With Malignant Pleural Mesothelioma · condition mapped ONTOLOGY_EXACT · 19 trials mapped (5 active)

—

Pleural Epithelioid Mesothelioma

Observed

clinicaltrials

graph →

→ studied in

NCT00365053Phase 2 · completed

PXD101 as Second-Line Therapy in Treating Patients With Malignant Mesothelioma of the Chest That Cannot Be Removed By Surgery · condition mapped ALIAS · 19 trials mapped (5 active)

—

Epithelioid Mesothelioma

Observed

clinicaltrials

graph →

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