Dedifferentiated Liposarcoma — knowledge graph · CancerIndex

Knowledge graph · Cancer

Dedifferentiated Liposarcoma

subtype

Identifier: CI-CAN-00002499
Entity page: /cancer/dedifferentiated-liposarcoma ↗
Edges: 58

Neighbours: 23 drugs10 trials
Drawn: 33 of 33 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Dedifferentiated Liposarcoma investigated in trials for …INVESTIGATED_IN_TRIALSderived23 of 23show fewer
→ investigated in trials for	Doxorubicinsmall molecule 5 trials (4 active) · roll-up of the cancer and its descendants	—	—	Dedifferentiated Liposarcoma	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Abemaciclibsmall molecule

Dedifferentiated Liposarcoma studied in …STUDIED_INderived10 of 35show all (up to 200)
→ studied in	NCT06498648Phase 1/Phase 2 · recruiting Testing the Addition of an Anti-cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (Gemcitabine) for Soft Tissue Sarcoma · condition mapped CURATED_BROADER · 35 trials mapped (20 active)	—	—	Dedifferentiated Liposarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06422806Phase 3 · recruiting Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas · condition mapped CURATED_BROADER · 35 trials mapped (20 active)	—	—	Dedifferentiated Liposarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05694871Phase 2 · active not recruiting Testing the Addition of Cemiplimab to Palbociclib for the Treatment of Advanced Dedifferentiated Liposarcoma · condition mapped CURATED_BROADER · 35 trials mapped (20 active)	—	—	Dedifferentiated Liposarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06025747Phase 1 · recruiting A Phase 1 Study of Neoadjuvant Abemaciclib in Combination With Radiation Therapy for Liposarcomas · condition mapped ONTOLOGY_EXACT · 35 trials mapped (20 active)	—	—	Dedifferentiated Liposarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06843967Phase 1/Phase 2 · recruiting A Study of Mirdametinib in Combination With Palbociclib in People With Liposarcoma · condition mapped ONTOLOGY_EXACT · 35 trials mapped (20 active)	—	—	Dedifferentiated Liposarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07802652Phase 2 · not yet recruiting Doxorubicin With or Without DT-7012 in Advanced Soft Tissue Sarcoma · condition mapped ONTOLOGY_EXACT · 35 trials mapped (20 active)	—	—	Dedifferentiated Liposarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03307616Phase 2 · active not recruiting Nivolumab With and Without Ipilimumab and Radiation Therapy in Treating Patients With Recurrent or Resectable Undifferentiated Pleomorphic Sarcoma or Dedifferentiated Liposarcoma Before Surgery · condition mapped ONTOLOGY_EXACT · 35 trials mapped (20 active)	—	—	Dedifferentiated Liposarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05711615Phase 1 · recruiting Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma · condition mapped CURATED_BROADER · 35 trials mapped (20 active)	—	—	Dedifferentiated Liposarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06389799Phase 2 · recruiting A Phase 2, Open Label Study of PEmigatinib and REtifanlimab in Advanced Dedifferentiated LIposarcoma (PERELI) · condition mapped ONTOLOGY_EXACT · 35 trials mapped (20 active)	—	—	Dedifferentiated Liposarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06975293Phase 1/Phase 2 · recruiting STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers and as Monotherapy in Participants With Selected Sarcomas · condition mapped ONTOLOGY_EXACT · 35 trials mapped (20 active)	—	—	Dedifferentiated Liposarcoma	1	Observed	clinicaltrials	graph →