Colorectal Signet Ring Cell Adenocarcinoma — knowledge graph · CancerIndex

Knowledge graph · Cancer

Colorectal Signet Ring Cell Adenocarcinoma

subtype

Identifier: CI-CAN-00005031
Entity page: /cancer/colorectal-signet-ring-cell-adenocarcinoma ↗
Edges: 38

Neighbours: 14 drugs10 trials
Drawn: 24 of 24 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Colorectal Signet Ring Cell Adenocarcinoma investigated in trials for …INVESTIGATED_IN_TRIALSderived14 of 14
→ investigated in trials for	Fluorouracilsmall molecule 13 trials (0 active) · roll-up of the cancer and its descendants	—	—	Colorectal Signet Ring Cell Adenocarcinoma	13	Observed	clinicaltrials	graph →
→ investigated in trials for	Leucovorinsmall molecule 11 trials (0 active) · roll-up of the cancer and its descendants

Colorectal Signet Ring Cell Adenocarcinoma studied in …STUDIED_INderived10 of 24show all (up to 200)
→ studied in	NCT01871571Phase 2 · terminated Bevacizumab, Fluorouracil, Leucovorin Calcium, and Oxaliplatin Before Surgery in Treating Patients With Stage II-III Rectal Cancer · condition mapped ALIAS · 24 trials mapped (0 active)	—	—	Rectal Signet Ring Cell Adenocarcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT01652196Phase 2 · completed Aflibercept and FOLFOX6 Treatment for Previously Untreated Stage IV Colorectal Cancer · condition mapped ALIAS · 24 trials mapped (0 active)	—	—	Rectal Signet Ring Cell Adenocarcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT01814501Phase 2 · completed Panitumumab and Chemotherapy in Patients With Advanced Colorectal Cancer After Prior Therapy With Bevacizumab · condition mapped ALIAS · 24 trials mapped (0 active)	—	—	Rectal Signet Ring Cell Adenocarcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02132858completed Genetic Mutations in Blood and Tissue Samples in Predicting Response to Treatment in Patients With Locally Advanced Rectal Cancer Undergoing Chemoradiation · condition mapped ALIAS · 24 trials mapped (0 active)	—	—	Rectal Signet Ring Cell Adenocarcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT00745134Phase 2 · terminated Radiation Therapy and Capecitabine With or Without Curcumin Before Surgery in Treating Patients With Rectal Cancer · condition mapped ONTOLOGY_EXACT · 24 trials mapped (0 active)	—	—	Rectal Signet Ring Cell Adenocarcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02232152Phase 1 · completed CPI-613 and Fluorouracil in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed by Surgery · condition mapped ALIAS · 24 trials mapped (0 active)	—	—	Rectal Signet Ring Cell Adenocarcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT01285102Phase 1 · terminated Chemoembolization Using Irinotecan in Treating Patients With Liver Metastases From Metastatic Colon or Rectal Cancer · condition mapped ALIAS · 24 trials mapped (0 active)	—	—	Rectal Signet Ring Cell Adenocarcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02270606Phase 1 · completed Phase I Study of Neoadjuvant Radiotherapy With 5-Fluorouracil for Rectal Cancer · condition mapped ALIAS · 24 trials mapped (0 active)	—	—	Rectal Signet Ring Cell Adenocarcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT01643499Phase 1 · completed Genotype-guided Dosing of mFOLFIRINOX Chemotherapy in Patients With Previously Untreated Advanced Gastrointestinal Malignancies · condition mapped ALIAS · 24 trials mapped (0 active)	—	—	Rectal Signet Ring Cell Adenocarcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT01802320Phase 2 · completed Akt Inhibitor MK2206 in Treating Patients With Previously Treated Colon or Rectal Cancer That is Metastatic or Locally Advanced and Cannot Be Removed by Surgery · condition mapped ONTOLOGY_EXACT · 24 trials mapped (0 active)	—	—	Colon Signet Ring Cell Adenocarcinoma	1	Observed	clinicaltrials	graph →